The NousCom team is lead by experienced enterpreneurs that worked together for many years in previous successful enterprises, such as Okairos, under the leadership of Prof. Riccardo Cortese, who conceived the ideas behind those companies.
The technology platform developed by Okairos is based on recombinant primates’ Adenovirus and Modified Vaccinia Virus Ankara (MVA) expressing antigens from infectious agents. Application of this technology led to novel vaccines targeting HCV, Malaria, RSV and Ebola among others. These products have been evaluated in more than 4,000 subjects of all ages including adults, newborns and elderly healthy volunteers, as well as patients suffering from chronic infectious diseases.
Building on previous experience and successes, NousCom has developed novel viral vectors, similar to the ones tested in the clinic against infectious diseases, encoding neoantigens for the treatment of cancer. Tumor neoantigens are believed to be potent immunogens with low risk of inducing autoimmunity that are detected by the immune system as “non-self” antigens, very similar to exogenous pathogens.